Bioengineering at Wayne State University

Welcome to Bioengineering

located at:
818 W. Hancock
Detroit MI 48202


8994

The Bioengineering Center of Wayne State University is a leading laboratory doing research work in the areas of impact trauma, low back pain and orthopedic biomechanics. Current projects in impact trauma include research on side impact, rear end collisions, head injury and lower extremity injuries. Our work in low back pain looks for causes of back pain and utilizes methods in neurophysiology to determine the source of pain in intervertebral joints. In orthopedic biomechanics, we are working on the causes of hip and vertebral fracture among the elderly, properties of bone as measured by acoustic microscopy and transmission ultrasound, and computer-aided insertion of pedicle screws. We offer a graduate program in Bioengineering through the College of Engineering. Students can pursue MS and PhD degrees in Mechanical or Electrical/Computer Engineering and major in Bioengineering.

Contact Person:

Albert I. King, Director
Wayne State University
Bioengineering Center
818 W. Hancock
Detroit, MI 48202
(313) 577-1347
(313) 577-8333 (Fax)
king@rrb.eng.wayne.edu

Courses offered in Bioengineering:


ME510 - Engineering Phisiology
ME516 - Biomechanics I
ME517 - Design of Rehabilitation Systems
ME518 - Introduction to Biomaterials
ME618 - Bioinstrumentation
ME710 - Mathematical Modeling in Bioengineering
ME716 - Biomechanics II
ME718 - Biomaterials II

55 YEARS of BIOENGINEERING


Wayne State University is a pioneer in bioengineering research. This interdisciplinary effort between the College of Engineering and the School of Medicine developed in 1939, when engineer H.R. Lissner and neurosurgeon E.S. Gurdjian initiated a collaborative effort to study the mechanisms of head injury. Although their methods were crude by today's standards, their unique cooperative effort has prospered to this day. It has given Wayne State University the honor of becoming the first institution in the U.S. to perform world renowned research in impact biomechanics.

Today's principal areas of research are biodynamic response to impact acceleration, spinal biomechanics, and human trauma research. Foremost among the goals of the center is the reduction of highway fatalities and major injuries. Many of the major research projects of the center have been related to automotive safety standards.

RESEARCH FACILITIES


The impact laboratory of the Bioengineering Center has a pneumatically driven sled code-named WHAM III (Wayne Horizontal Accelerator Mechanism). It is used for the simulation of vehicular crashes and is equipped with a concrete barrier. It can be used to produce car-to-car, frontal, rear, and side impact, roll-over simulations and moving barrier tests. Over 60 channels of data can be acquired during a single impact.

The Center also has a linear impactor for carrying out regional impacts to various body segments. Associated equipment includes high-speed film, cameras, test dummies and instrumentation to measure acceleration and load. The Center is also equipped with a bi-axial Instron materials testing machine for use in measuring the strength of biological materials.

An Ultrasound Applications Lab has been initiated at the Bioengineering Center for the characterization of the material properties of biological tissues. The lab contains an acoustic microscope, which is a high resolution ultrasonic device designed to map the elastic properties of hard tissues by measuring the reflection of sound from the material surface. The present research focus is for the development of a quantitative measure of stiffness from acoustic images. Transmission ultrasound equipment is used to assess the mechanical and structural properties of materials. Facilities are available for the preparation of specimens for ultrasonic and optical examination.

Hutzel Hospital supports a Biomechanics Laboratory under the direction of Drs. Michele Grimm and Sheu-Jane Shieh. This lab, which contains a bi-axial Instron materials testing machine, a portable x-ray machine, and a complete set of EMG devices to measure the activities of up to 10 muscles simultaneously. There is a precision stadiometer to measure spinal height. The laboratory is also equipped with a high pressure air saw and drill system with all the surgical instruments necessary for artificial hip and knee replacement.

A complete computer facility is available linking several SUN workstations to the School of Medicine and the College of Engineering via a high speed fiber optic link.

RESEARCH PROGRAMS


Under governmental and industrial sponsorship, the Center is engaged in side impact research which seeks to establish human response and tolerance to impact. Examples include the testing of padding of suitable stiffness to determine its value as protection in a side impact collision. A mathematical model has been developed to aid in the design of side structures of automobiles for optimal protection of their occupants. Other projects include the study of the potential of injuries from restraint systems, such as the air bag or injuries to the extremities from a knee bolster.

The study of closed head injury is a very important area of research taking place at the Center. Brain injury continues to be the most difficult and expensive injury problem in America. The National Center for Injury Prevention and Control of the Centers for Disease Control sponsors a program to study the effects of brain motion following a blunt impact. The outcome of studying brain motion from head impacts on human cadavers will result in the development of a realistic finite element model which will be used to closely mimic the experimentally observed brain motion. This study seeks to correlate this brain motion with diffuse axonal injury as seen in victims of head injury.

A third significant area of research conducted at the Center is that of low back pain (LBP). Under the direction of Dr. John M. Cavanaugh, several areas have been identified within the intervertebral joint where a combination of mechanical stretch and the presence of pain fibers can cause LBP, particularly on the facet joint capsule. Neurophysiological studies are being conducted to isolate the specific sources which produce the inflammatory process and the initiation of low back pain.

A new area of research is the study of bone mechanics by non-destructive measurements of material properties. One research initiative is focused on the development of a better understanding of the fundamental structure-function relationships in biological tissues with the use of novel acoustic microscopy techniques. These techniques may be used for high resolution, micro-scale measurements of the mechanical properties of bones as well as for musculoskeletal research where quantitative analysis of functional integrity is required.

Finally, sports biomechanics deals with the protection of athletes from injury to the head, neck, chest and extremities. For example, the Center studies and evaluates the effectiveness of prophylactic knee braces in preventing football related knee injuries. It has also been a leader in developing helmet standards for head and neck injury protection. The center continues to provide helmet and turf evaluations.

BIOENGINEERING STAFF


The Bioengineering Center is administered by the College of Engineering and draws its faculty from both the College of Engineering and the School of Medicine. It is directed by Dr. Albert I. King who has been engaged in biomechanical research for 35 years.
The Center is staffed by over 30 full-time and part-time personnel, over half of which are graduate and undergraduate students.

RESEARCH STAFF AND FULL TIME FACULTY


Albert I. King, Ph.D.
king@rrb.eng.wayne.edu

Impact biomechanics, low back pain

Paul C. Begeman, Ph.D.
begeman@rrb.eng.wayne.edu

Impact biomechanics, neck and ankle injuries

John M. Cavanaugh, M.D.
cavanau@rrb.eng.wayne.edu

Side impact, low back pain

Timothy Walilko, M.S.
walilko@rrb.eng.wayne.edu Click here to mail

Sports biomechanics

Sheu-Jane Shieh, Ph.D.
shieh@rrb.eng.wayne.edu

Acoustic microsopy of bone, orthopaedic biomechanics

King-Hay Yang, Ph.D.
yang@rrb.eng.wayne.edu

Finite element modelling, impact & orthopaedic biomechanics

Michele J. Grimm, Ph.D.
grimm@rrb.eng.wayne.edu

Orthopaedic biomechanics, ultrasound characterization of bone


CDC Injury Prevention through Biomechanics Symposium

Each year Wayne State University's Bioengineering Center hosts the CDC sponsored Injury Prevention through Biomechanics Symposium at Hutzel Hospital on Wayne State's Medical School campus. Information on the current year's symposium is available.


Other Bioengineering Sites

Mueller Institute of Biomechanics

Canadian Reference Place

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